Jean-Christophe Roux

Jean-Christophe ROUX (MMG) achieved his academic education at Claude Bernard University in Lyon France, where he obtained a PhD in Physiology. As a postdoc at the Karolinska Institute, he participated in research on the development of respiratory control at birth and how environmental perturbations could affect it. As part of the human neurogenetics team led by Dr Laurent Villard, Jean-Christophe Roux has been in charge of Rett Syndrome and associated pathologies since 2006.  His group is studying mouse models of Mecp2 dysfunctions and his work led to the implementation of two clinical trials (phase 2a) with Rett patients. The first trial deals with the stimulation of the monoaminergic neurotransmission and the second with the trophic support. Recently, he has developed innovative approaches using gene therapy targeting the brain.